Formaldehyde exposure in medical students: a short period of contact causes DNA damage and instability
Abstract— Occupational exposure to formaldehyde (FA) has been related to adverse outcomes. However, a short period of exposure has never been assessed in terms of evaluating DNA. This study conducted on 39 medical students exposed to FA in a university laboratory of human anatomy and aimed to analyze the relationship between FA exposure and DNA damage. The buccal micronucleus cytome assay (BMCyt) was used to evaluate the students at four time points: before FA exposure, after four months of FA exposure, after eight months of FA exposure and after three months without FA exposure (remission period). Pyknotic cells, karyolitic cells, karyorrhetic cells, condensed chromatin, binucleated cells, basal cells differentiated cells, micronucleated cells and nuclear bridges were enumerated. This study shows that FA exposure caused genomic instability in all periods and the remission period was not sufficient to reverse all damage. Thus, prolonged occupational exposure to FA not only causes DNA damage but a shorter exposure period can have the same effect.
Keywords— Buccal MNi, DNA Damage, Formaldehyde Exposure, Genome Instability, Medical Students.
Abstract—Myiasis is a rare disease by developing larvae (Maggots) of a variety of fly species within the arthropod order Diptera. Recognition and Management of Myiasis are demanding. Herein we present a 7-months-old Saudi girl presented with multiple skin lesions over her body, clinical diagnosis of skin abscess was made initially. Incision revealed multiple maggots coming from the incision wounds, the larva was extracted and the clean dressing was done. Patient showing complete recovered skin infection. Cutaneous Myiasis is a devastating presentation of a variety of fly species that should be considered in the appropriate clinical setting and recent traveling to the suspicious area.
Keywords— Cutaneous Myiasis, Dermatobiahominis.
Abstract—Diabetes is a disease which is on continuous increase specialy in country like India. It involve is a multisystem so intend to affect quality of life of patients. So this study was conducted on 250 Diabetes Mellitus patients to observe their quality of life on various domains viz Physical, Mental, Social and environmental through WHOQOL-Bref questionnaire. It was found that 54.4% were unable to level their quality of life, they say neither good nor bad. But 23.2% were feeling bad and 22.4 % were feeling good about their quality of life. Whereas regarding patient's satisfaction about their health 39.2% were unable to level their quality of life and 35.6% were dissatisfied and 25.2 % were satisfied with their health. Significantly more cases were unable to understand about their quality of life than their satisfaction to their health. It was also found that Physical quality of life was affected most followed by environmental, psychological and social dimension of quality of life.
Keywords— Diabetes Mellitus, Quality of Life, WHOQOL-Bref.
Standard precautions Status of Nursing Personnel’s of Tertiary Level Care Hospital of Rajasthan: A Descriptive Analysis
Abstract—In India, communicable diseases account for nearly half of its disease burden. Nursing staff plays a major role in the health care delivery system; therefore their role in prevention of infectious diseases by taking care of universal precautions is very important. So this study was conducted aimed to know the status of universal precaution practices of nursing personnel of a tertiary care hospital of Rajasthan. 100 nursing professionals were interrogated and supervised for practice and as per a semi- structured schedule. It was concluded from this study that all nursing personals were washing hands after toilet and hands were washed properly but they were reluctant regarding every time washing hands before starting work, washing with antiseptic after contacting contaminated gauze, linen etc. Apron was weared by 89% but none was wearing mask while dealing with patients. And only 40% were wearing gloves while handling patient but none was changing gloves before handling new patient. It was also concluded that all the nursing personals were using sterile syringes and new syringe was taken every time for new patients which was destroyed after use but only 43% were wearing glove while taking out needle/syringes from its wrapper and only 29% nursing personals were recapping syringes after use. Proper disposal of syringes, soiled infected gauze, needles, I.V. Drip set and gloves was done by almost all nursing personals
Key words- Nursing Personnel. Universal Precautions, Practice
Abstract— Dental diseases are health problem of developing countries mainly because of the fact that in developing countries these diseases are given less importance. People also not much bothered about children's personal hygiene and dental diseases until it leads to toothache and disability. And at this time it may lead to complication and expensive treatment. So a community based study was conducted in rural area of Jaipur district to find out the association between dental diseases and personal hygiene. From schools of Amer tahsil of Jaipur district 1600 students were examined for dental diseases and interrogated and observed for personal hygiene. Association of personal hygiene with dental diseases like Dental Carries, Dental Fluorosis, Malocclusion and Periodontitis was found out with chi-square test. It was revealed that Dental diseases like Dental Carries, Dental Fluorosis, Malocclusion and peridontitis all are associated with personal hygiene. Dental carries increases as the personal hygiene worsen and likewise same was observed with Malocclusion but Dental Fluorosis was observed in inverse direction mean as the personal hygiene improves the chances to have Dental Fluorosis increases. Periodontal it was found significantly more when personal hygiene of child is either poor or good, when it is fair chances of having Periodontal diseases were significantly less.
Keywords— Dental Carries, Personal Hygiene, Dental Fluorosis, Malocclusion, Periodontitis
Abstract— Bronchial Asthma is a public health problem in childhood. Allergic Rhinitis (AR) is a very common co-morbidity with Bronchial Asthma. So this study was conducted on 250 Primary School Children to find prevalence of Bronchial asthma and Allergic Rhinitis and their association. It was observed from this study that 17.2% of children were having Bronchial asthma and 20.4% were found to have allergic Rhinitis. Co morbidity of Bronchial Asthma with Allergic Rhinitis was observed in 11.6 % of these cases. It was also observed that Bronchial Asthma was observed significantly more in males than females and children of walled city than outer city. So it was concluded form this study that chances of occurring Allergic Rhinitis is significantly more with Bronchial Asthma than the chances of Bronchial Asthma with Allergic Rhinitis
Keywords— Bronchial Asthma, Allergic Rhinitis, School Children