Saturday, 31 December 2016

IMJ Health : December 2016

Medical Journal: published its volume-2, Issue-12, December 2016 with AD Publications

Experiencing Social Marketing: An Attitudinal Study on Family Planning in Addis Ababa, Ethiopia

Abstract— Issue of family planning has gained attention due to its importance in decision-making about population growth and areas related to the overall socio-economic development of a nation. Social marketing, on the other hand, has gained popularity in addressing issues related to change in social behaviors such as family planning, and particular to developing nations like Ethiopia. This study makes an attempt to relate the idea of social marketing, as an approach of bringing attitudinal changes in the behaviors of individuals toward the concept of family planning and usage of contraceptives. Specifically, the objectives include an examination of the role of social marketing-mix in family planning experiences and to compare the attitudes of men and women toward family planning.

In order to gather the primary data, structured (draft) questionnaire was prepared and tested through a pilot-study (with 35 respondents). The final survey comprises 150 respondents, selected accidently by having a quota of 50% for each gender. Factor and reliability analysis were used to test the validity and reliability of the scale items. The result revealed that attitude towards family planning and contraceptives usage found being highly affected by the awareness and responsibility towards society/service usage. Therefore, as the marketing activities like promotion increases, awareness is expected to increase, which finally determines favorable attitude towards family planning products/techniques (e.g., contraceptives).

Keywords: Social Marketing, Family Planning, Contraceptives, Attitudes, Behavior, Ethiopia.

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Status of qnr and aac(6’)-lb-cr Genes in Quinolone-Resistant Non-Fermenters

Abstract— Non-fermenters are aerobic non-spore forming Gram-negative bacilli that either incapable of catabolized carbohydrates as a source of energy or degrade them via oxidative rather than fermentative metabolic pathways. In the group of non-fermenters Pseudomonas aeruginosa is eminent pathogen followed by Acinetobacter baumanni. Both of these organisms are reported for their intrinsic resistance against antibiotics and their ability to acquire gens that encode resistance. Resistant against quinolones like ciprofloxacin is common against Gram’s negative non-fermenters. For most of the mechanism of resistant in both of these organisms against quinolone, is the production of aminoglycoside modifying enzymes, mutations in topoisomerases, up-regulation of efflux pumps and presence of plasmid mediated qnr genes. In this study, during the study period total 94 non-fermenters were isolated from 378 numbers of different clinical specimens. Out of 94; 21 isolates were found resistant against quinolone antibiotics like ciprofloxacin-5 µg, levofloxacin-5 µg , norfloxacin-10 µg, which were subjected for PCR studies to detect resistant genes, only five (23.81%) isolates were found to be associated with aac(6’)-lb-cr and two (9.52%) were found positive for carrying qnrD gense as additional with aac(6’)-lb-cr genes. Organisms that processed qnrD and aac(6’)-lb-cr gens were, Pseudomona aeruginosa, Acinetobacter baumanni , Alcaligenes faecalis , Acinetobacter calcoaceticus, and Pseudomonas sp.

Key word: Non-fermenters, Quinolone resistant, PCR studies, QNR, aac(6’)-Ib-cr.

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Knowledge Status of Accredited Social Health Activist (ASHA) of Jaipur City

AbstractGovernment of India launched the National Rural Health Mission (NRHM) on 12th April 2005, to provide accessible, accountable, affordable, effective and reliable primary health care, especially to the poor and vulnerable sections of the population. And ASHAs are a ‘bridge’ or an interface between the community and health service outlets. NHM set some standard for ASHAs. So this study was conducted to assess the knowledge of ASHA of Jaipur city. This cross-sectional study was conducted on 172 ASHAs working in Jaipur city. In the present study, all the ASHAs know their role about Immunization, Ante Natal Care and to inform Sub Centre/PHC/CHC about births and deaths in the village & outbreak of health problem/disease in the community. The majority (>80%) ASHAs knew their role in Post Natal Check-up, counseling women for Birth preparedness, safe delivery, exclusive Breast feeding, complementary feeding, Personal hygiene and sanitation. Promoting hand washing after toilet and before food handling was known to 153 (88.95%) of ASHAs. It was concluded from the study that majority of ASHAs know their role and details of their practices in all expected field except regarding basic sanitation and hygiene. Knowledge of ASHAs regarding their role about basic sanitation and hygiene of community i.e. to 19.19% of ASHAs only. Likewise regarding promote construction of toilet was also known to only 17.44% of ASHAs. Even only 37.79% of ASHAs knew about immunization may be given in mild fever.

Key words: ASHA, Knowledge Status of ASHA.

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Comparative Outcome of Basi-Cervical Neck of Femur Fractures Fixed Using DHS with and without De-Rotation Screw

Abstract— Basicervical fracture necks of femur are intermediate between femur neck fracture and intertrochantric fracture. These fractures having axial and rotational instability are traditionally being treated with DHS. DHS allow solid fixation in two planes only, additional derotation screw allow stability in third plane also.

Objective: To compare outcome of basicervical fracture neck of femur treated with and without derotation screw.

Material and Methods: Patients were divided in two groups i.e. group 'A' and group 'B' each group having 30 patients. Group 'A' patients were treated with DHS with derotation screw and group 'B' patients with DHS alone.

Results: At 12 months postoperatively patients were clinically and radiologically evaluated. All frcture were united in Group 'A' within an average period of 12.5 week while three patients (10%) ended up in non-union in group 'B'. Mean sliding distance in group 'A' was 5.6 mm while it was 6.2 mm in group 'B'. Mean shortening of limb was 3.8 mm in group 'A' which was 4.3 mm in group 'B'. In group 'A' there was no major displacement between the fracture but in group B there was >3 mm displacement in five patients (16.66%). According to modified Harris hip score in group 'A' 26 patients (86.66%) had excellent results, two patients(6.66%)had good results, one patient(3.33%) had fair results and in one patient(3.33%)poor results was obtained.

Conclusions: It can be concluded from study that there were better radiological and clinical outcome in DHS with derotation screw than DHS alone in basicervical fracture neck of femur.

Key words: Basicervical fracture, DHS, Derotation screw.

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Tuesday, 6 December 2016

Medical Journal: November 2016 Issue

Medical Journal: AD Publication had published its Volume-2, Issue-11, November 2016 Issue with International Multispeciality Journal of Health (IMJ Health)

Outcome Analysis of Outpatient Total Knee and Total Hip Arthroplasty: A Follow up upto three Months

Abstract— Traditionally total knee and hip arthroplasty surgeries requires long duartion of hospital stay. More duration of stay has its own disadvantages. So it was tried to developed an accelerated clinical pathway for patients undergoing total knee arthroplasty (TKA) and total hip arthroplasty (THA) who are considered healthy enough for early discharge. Between March 2013 – April2014, 89 TKA and 116 THA were performed to different patients at a single institution by a single orthopedic surgeon. 71 (31 TKA, 40 THA) met the inclusion criteria for the study. All patients received 2 grams of tranexamic acid and 750 mg cefuroxime sodium intravenously at 30 minutes prior to surgery. A multi-modal protocol for perioperative pain management was used for all patients. Out of total 71 patients (12 males, 59 females) with a mean age of 59 years (range, 24-79 years). The mean length of hospital stay was 27,3 hours (range, 15-60 hours). The mean duration of surgery was 92 minutes (range, 75-128 minutes) for TKA, 72 minutes (range, 48-81 minutes) for THA. Combined spinal epidural anesthesia was performed in 55 patients (77%) and general anesthesia in 16 patients (23%). Of the total 71 patients, 51 (71,8%) were discharged within 23 hours after surgery. Only 11(15.5%) were re-addmitted because of minor complains. These results of this study demonstrated that early discharge does not result in significant complications related to the outpatient procedure in selected patients up to three months postoperatively.

Keywords: Outpatient, Total Hip Arthroplasty, Total Knee Arthroplasty, Anesthesia.

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Determination of patterns in the EEG signals during relaxation through music using Bayesian Networks

Abstract—Today it is known that the brain waves behave during relaxation through music, however, it is not yet known whether there is a pattern of dependencies between different EEG frequencies during those processes. Brain oscillations are often underestimated as compared to slower oscillations. Mean power spectra of scalp EEG signals exhibit distinct peaks emerging from the general decrease in power with increasing frequency, suggesting the existence of characteristic dependence oscillatory modes in cortical field potentials. The interactions between peaks in different frequency bands, within and between cortical EEG sources, are not well understood. The reviewed evidence supports the theory that relaxation through music can lead to behavioral and neuron chemical changes with benefic effects. This study was to address this concept by focusing on Bayesian Networks (BN) to describe the relationship between the EEG frequencies during relaxation through music. It was obtained a model with 97.7% to accuracy, in which shows the relations between each EEG signals. The dependency probability distribution was calculated, according to the signal amplitude behavior. Music changes the behavior of the low frequency signals, synchronizing them inversely proportional. Delta and theta interactions over Alpha promote increase Alpha 1 powers in relaxation through music. This event is accompanied by synchronized interaction of low-sequence signals, from Beta 1 to Gamma. Alpha 2 remains an independent variable. Further studies are needed to understand the differences between music and their subsequent effects on behavior. However, Bayesian Networks has been show to an excellent tool of EEG signal Analysis.

Key word: Bayesian Networks, Brain, Machine learning, Data mining.

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Fuzzy Inference Modeling of Risk Factors in Coronary Diseases : A Review

Abstract- To estimate the variation in the major risk factors for cardiovascular disease (Hemoglobin HGB; mean corpuscular volume MCV; Mean corpuscular hemoglobin concentration MCHC; Fe and Folic acid), we try preventing according coronary heart disease risk factors observed in elderly men and women in the region of Setif – Algeria. Participants.100 men and women aged 26 to 86 years for whom the physiological parameters were recorded. These parameters are risk factors for cardiovascular disease. The expected analysis was estimated using an artificial intelligence model including the principles of fuzzy logic. Risk factors are inputs of the system and the incidence of coronary heart disease is output. The observed data recorded from Analysis Central Laboratory of Setif university hospital - Algeria. Factors that promote coronary heart disease are inaccurate and uncertain. The effect of these factors varies from person to person. Their consideration as fuzzy variables is perfectly adequate. A database is established. Fuzzy inference rules are highlighted according to the recorded values. An algorithmic application is established making it possible to read instantly the number likely the person with a coronary disease just by the random introduction of the variables at the input of the system.

Keywords: Coronary diseases, Risk factors, Artificial intelligence, Fuzzy logic.

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Clinico-etiological profile of Empyema Thoracis in children: A Descriptive Analysis

Abstract—Empyema is an uncommon complication of childhood pneumonia. Although mortality rates in pediatric empyema are very low, empyema causes significant morbidity including substantial health care costs and burden of care. A descriptive observational study was conducted on 40 Empyema Thoracis in 0-12 years aged. Empyema was diagnosed as per “GOLDEN CRITERIA. Clinical profile including signs and symptoms was recorded with biosocial profile. Blood and Plural fluid examinations were also done. Microbiology and histo-pathological examinations were also done. Data collected were analysed, qualitative data were expressed in percentage and quantitative data were expressed in mean ± SD. Mean age of children was 5.01 years with slight female predominance (M:F = 2:3). Mean haemoglobine was 9.45 g/dl, Total leucocytes count (TLC) 17,293 with platelet counts 2.69 lakhs. PH of blood and plural fluid was 7.39 and 6.98 respectively. Cough was the most common complain (in 72%) followed by fever, breathlessness and chest pain. Likewise tackypnea was the most common sign elicited followed by pallor conjunctiva and cervical lymphadenopathy. On examination trachea was shifted either on right or left side in 52% cases, Creptations were observed in 72.5% of cases and Ronchi were observed in one (2.5%) case. Dullness on percussion, decrease air entry and decreased vocal resonance was observed in all the cases. Gram positive cocci and Gram negative bacilli were observed in 25% and 2.5% cases respectively. Out of these micro-organism, Streptococci, Staphylococci and Klebsela Pneumonae were found in 7.5%, 12.5% and 2.55 of cases respectively. Acute inflammation was found in 7.5%, chronic inflammation was found in 7% whereas Koch's was found in 18% of cases in histology.

Key word: Children, Empyema Thoracis, Clinico-Etiological Profile.

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Maternal polycystic ovary syndrome (PCOS) and Antenatal (ANC) Complications: A Case Control Study

Abstract Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women. Evidences shows variable finding regarding it's effect on pregnancy outcomes. This present study was conducted to determine whether maternal polycystic ovary syndrome (PCOS) is associated with adverse pregnancy outcomes in antenatal period. Prospective observational study, carried out in the department of Obstetrics and Gynecology, Indraprastha Apollo Hospitals, New Delhi, including 64 women with PCOS and 64 normal pregnant women between January 2013 and November 2014. It was found that Gestational diabetes mellitus (GDM) was significantly more frequent in the PCOS group than in the control group (p value = 0.009; OR=2.698 (1.213-6.001), this difference was not found statistically significant. Pregnancy induced hypertension (PIH) was also found significantly more frequent in the PCOS group than in the control group (p value=0.014; OR=3.41 (1.176-9.885). Miscarriage rate was not significantly different among two groups. So it can be concluded that women affected by PCOS carry an increased risk of adverse pregnancy outcomes specially GDM and PIH.

Key word: Polycystic ovary syndrome (PCOS), ANC Complications, GDM, PIH.

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Factors associated with Physical Quality of Life in Diabetes Mallitus

Abstract—Diabetes is a disease of development involving multisystem so intend to affect quality of life of patients in many ways i.e. Physical, Mental, Social and environmental. So this study was conducted on 250 Diabetes Mellitus patients to study their physical quality of life and its associating factors. It was found that 9.6% of diabetes patients had poor physical quality of life in this study. This physical quality of life is associated with education and socio-economic status of patient but not with age, sex and occupation. Physical quality of life was observed more poor in either illiterates or in secondary educated patients than their other counterparts. Likewise physical quality of life was observed more poor in Class III and IV than Class I, Class II and Class V.

Keywords Diabetes Mellitus, Physical Quality of Life.

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Friday, 4 November 2016

Medical Journal:: IMJ Health:: October 2016 Issue

Medical Journal: AD Publication had published its Volume-2, Issue-10, October 2016 Issue with International Multispeciality Journal of Health (IMJ Health)

Modeling and Preventive Measures of Ebola: An Analysis of an Epidemic in Libya

Abstract—Ebola is a rare virus, which can cause severe acute hemorrhagic fever and high mortality for humans and non-human primates. In 2014, Ebola virus out breaking in West Africa triggered a grave disaster to the people of the world, finally, it has been inhibited successfully under the vaccine and effective drug. In this article, data from patients and deaths due to Ebola were collected, which were reported by WHO. These data were analyzed and researched the spread of Ebola by SEIR model. In this model, basic reproduction number obtained was 15, which was based on the number of dead and patients from June to September in Libya. And according to the sensitivity analysis for basic reproduction number, it was proved that improving vaccination rate and recovery rate of infectious are two effective ways to suppress the spread of the Ebola epidemic. This article gives a detailed and direct scientific theory basis for the control of Ebola virus in the end.

Keywords Ebola, Differential Dynamic Equations, Basic Reproduction Number.

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Menstruation and Menstrual hygiene among Adolescent girls of Ahmadabad city: A Descriptive Analysis

Abstract—Adolescence proves to be the most vulnerable phase in the path of human life cycle after infancy. Adolescent Girls (AGs) have many issues related to menstruation which is seldom addressed. Unhygienic practices during menstruation endanger the reproductive health and well being of AGs. Hence, a study was undertaken to assess the reproductive health status of Adolescent AGs.

Methodology: A cross-sectional study was carried out among 467 AGs attending Adolescent Friendly Health Service (AFHS) clinics in Ahmadabad city during May 2011 to august 2012.

Result: Mean age of AGs was 14.5+2.4 years. Out of 467 AGs, 296 (63.3%) had attained Menarche. Mean age at Menarche was 13.31+1.31 years in this study (Fig 1). Source of information regarding menstrual cycle was mother in 77.7% AGs in this study. Dysmenorrhea was present in 59.9% AGs. Dysmenorrhea was seen in 107(67.3%) AG in the late adolescence, 68(53.1%) in mid adolescence and 2(22.2%) in early adolescence. The difference in occurrence of Dysmenorrhea observed in different phases of adolescence was significant (χ2=37.423,Df=2,p<0.0001). Pre-menstrual tension was complained by 27.7% AGs and Vulval pruritus by 2% AGs.

Conclusion: This study highlights the need of AGs to have correct and complete information regarding menstruation at appropriate age from formal channels of communication which is mother in this case. Informal channels such as friends and sister tends to increase the misconception and improper menstrual hygiene which could make the AGs vulnerable to infection.

Keywords Adolescent girls, Menstruation, Dysmenorrhea.

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Superior Orbital Fissure Syndrome due to Metastatic Prostatic Malignancy – A Case Report

Abstract— A 56 years old male patient, a known case of prostatic malignancy with skeletal metastasis presented with ptosis, exotropia, diminished pupillary reflex and limitations in extra-ocular movements of left eye. MRI brain revealed diffuse skull base and leptomeningeal metastasis. Whole body CT scan showed metastasis in ribs, scapula and in pelvic bones. He was diagnosed to have superior orbital fissure syndrome due to metastatic prostatic malignancy and was offered steroids and radiotherapy.

Key Words: Ptosis, Prostate, Metastasis.

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Sex determination using mastoid process measurements of dry skull bone: A Descriptive Analysis

Abstract—Study on human skeletal for sex determination has been a topic of interest among researchers. It appears to be the main reliable bone exhibiting sexually dimorphic traits, specially the mastoid region. Present study aims to determine the difference in mastoid morphometry between male and female bone for sex differentiation.

Material and methods: A descriptive observational study was conducted at Department of Anatomy, SMS Medical College, Jaipur between April- December 2014. Forty dry macerated adult Human skulls of age group above 18-25 yrs of known sex were included in which suture between the basiocciput and basisphenoid were united. Vernier Caliper was used for measurements of Mastoid process in Frankfurt’s Plane.

Results: Mastoid length was significantly larger in males as compared to females on both sides (p value <0.05). Cut-off of right mastoid length of 32.39mm and left Mastoid length of 31.71mm were highly accurate in differentiating male and female skull.

Conclusion: The parameters like mastoid process length can be used as predictors to determine gender and could be of immense use in forensic medicine and anthropology and will also serve as a future framework for estimating the craniofacial dimensions of other Indian population.

Key word: Mastoid Length, Sex Differentiation, Sex Determination.

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Saturday, 1 October 2016

IMJ Health : September 2016

General Medicine, General Surgery, Gynecology & Obstetrics, Pediatrics, Anesthesia, Ophthalmology, Orthopedics, Otorhinolaryngology (ENT), Physical Medicine & Rehabilitation, Dermatology & Venereology, Psychiatry, Radio Diagnosis, Cardiology Medicine, Cardiothoracic Surgery, Neurology Medicine, Neurosurgery, Pediatric Surgery, Plastic Surgery, Gastroentrology, Gastrointestinal Surgery, Pulmonary Medicine, Immunology & Immunogenetics, Transfusion Medicine (Blood Bank), Hematology, Biomedical Engineering, Biophysics, Biostatistics, Biotechnology, Health Administration, Health Planning and Management, Hospital Management, Nephrology, Urology, Endocrinology, Reproductive Biology, Radiotherapy, Oncology and Geriatric Medicine

Formaldehyde exposure in medical students: a short period of contact causes DNA damage and instability

Abstract Occupational exposure to formaldehyde (FA) has been related to adverse outcomes. However, a short period of exposure has never been assessed in terms of evaluating DNA. This study conducted on 39 medical students exposed to FA in a university laboratory of human anatomy and aimed to analyze the relationship between FA exposure and DNA damage. The buccal micronucleus cytome assay (BMCyt) was used to evaluate the students at four time points: before FA exposure, after four months of FA exposure, after eight months of FA exposure and after three months without FA exposure (remission period). Pyknotic cells, karyolitic cells, karyorrhetic cells, condensed chromatin, binucleated cells, basal cells differentiated cells, micronucleated cells and nuclear bridges were enumerated. This study shows that FA exposure caused genomic instability in all periods and the remission period was not sufficient to reverse all damage. Thus, prolonged occupational exposure to FA not only causes DNA damage but a shorter exposure period can have the same effect.

Keywords Buccal MNi, DNA Damage, Formaldehyde Exposure, Genome Instability, Medical Students.

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Cutaneous Myiasis in Saudi Infant: A Rare Case Report

Abstract—Myiasis is a rare disease by developing larvae (Maggots) of a variety of fly species within the arthropod order Diptera. Recognition and Management of Myiasis are demanding. Herein we present a 7-months-old Saudi girl presented with multiple skin lesions over her body, clinical diagnosis of skin abscess was made initially. Incision revealed multiple maggots coming from the incision wounds, the larva was extracted and the clean dressing was done. Patient showing complete recovered skin infection. Cutaneous Myiasis is a devastating presentation of a variety of fly species that should be considered in the appropriate clinical setting and recent traveling to the suspicious area.

Keywords Cutaneous Myiasis, Dermatobiahominis.

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Quality of Life in Diabetes Mallitus patients: A Descriptive Analysis

Abstract—Diabetes is a disease which is on continuous increase specialy in country like India. It involve is a multisystem so intend to affect quality of life of patients. So this study was conducted on 250 Diabetes Mellitus patients to observe their quality of life on various domains viz Physical, Mental, Social and environmental through WHOQOL-Bref questionnaire. It was found that 54.4% were unable to level their quality of life, they say neither good nor bad. But 23.2% were feeling bad and 22.4 % were feeling good about their quality of life. Whereas regarding patient's satisfaction about their health 39.2% were unable to level their quality of life and 35.6% were dissatisfied and 25.2 % were satisfied with their health. Significantly more cases were unable to understand about their quality of life than their satisfaction to their health. It was also found that Physical quality of life was affected most followed by environmental, psychological and social dimension of quality of life.

Keywords Diabetes Mellitus, Quality of Life, WHOQOL-Bref.

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Standard precautions Status of Nursing Personnel’s of Tertiary Level Care Hospital of Rajasthan: A Descriptive Analysis

Abstract—In India, communicable diseases account for nearly half of its disease burden. Nursing staff plays a major role in the health care delivery system; therefore their role in prevention of infectious diseases by taking care of universal precautions is very important. So this study was conducted aimed to know the status of universal precaution practices of nursing personnel of a tertiary care hospital of Rajasthan. 100 nursing professionals were interrogated and supervised for practice and as per a semi- structured schedule. It was concluded from this study that all nursing personals were washing hands after toilet and hands were washed properly but they were reluctant regarding every time washing hands before starting work, washing with antiseptic after contacting contaminated gauze, linen etc. Apron was weared by 89% but none was wearing mask while dealing with patients. And only 40% were wearing gloves while handling patient but none was changing gloves before handling new patient. It was also concluded that all the nursing personals were using sterile syringes and new syringe was taken every time for new patients which was destroyed after use but only 43% were wearing glove while taking out needle/syringes from its wrapper and only 29% nursing personals were recapping syringes after use. Proper disposal of syringes, soiled infected gauze, needles, I.V. Drip set and gloves was done by almost all nursing personals

Key words- Nursing Personnel. Universal Precautions, Practice

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Association of Dental Diseases with Personal Hygiene in School Children of Rural Rajasthan, India

Abstract— Dental diseases are health problem of developing countries mainly because of the fact that in developing countries these diseases are given less importance. People also not much bothered about children's personal hygiene and dental diseases until it leads to toothache and disability. And at this time it may lead to complication and expensive treatment. So a community based study was conducted in rural area of Jaipur district to find out the association between dental diseases and personal hygiene. From schools of Amer tahsil of Jaipur district 1600 students were examined for dental diseases and interrogated and observed for personal hygiene. Association of personal hygiene with dental diseases like Dental Carries, Dental Fluorosis, Malocclusion and Periodontitis was found out with chi-square test. It was revealed that Dental diseases like Dental Carries, Dental Fluorosis, Malocclusion and peridontitis all are associated with personal hygiene. Dental carries increases as the personal hygiene worsen and likewise same was observed with Malocclusion but Dental Fluorosis was observed in inverse direction mean as the personal hygiene improves the chances to have Dental Fluorosis increases. Periodontal it was found significantly more when personal hygiene of child is either poor or good, when it is fair chances of having Periodontal diseases were significantly less.

Keywords Dental Carries, Personal Hygiene, Dental Fluorosis, Malocclusion, Periodontitis

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Association between Bronchial asthma and Allergic Rhinitis: A Cross-sectional Study

Abstract— Bronchial Asthma is a public health problem in childhood. Allergic Rhinitis (AR) is a very common co-morbidity with Bronchial Asthma. So this study was conducted on 250 Primary School Children to find prevalence of Bronchial asthma and Allergic Rhinitis and their association. It was observed from this study that 17.2% of children were having Bronchial asthma and 20.4% were found to have allergic Rhinitis. Co morbidity of Bronchial Asthma with Allergic Rhinitis was observed in 11.6 % of these cases. It was also observed that Bronchial Asthma was observed significantly more in males than females and children of walled city than outer city. So it was concluded form this study that chances of occurring Allergic Rhinitis is significantly more with Bronchial Asthma than the chances of Bronchial Asthma with Allergic Rhinitis

Keywords Bronchial Asthma, Allergic Rhinitis, School Children

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Thursday, 1 September 2016

Medical Journal: IMJ Health: Volume-2, Issue-8, August 2016

Medical Journal: Volume-2, Issue-8, August 2016

Critical Review of Different Sociological Perspectives toward Conceptualization of Management of Health Services

Abstract—Theories of sociology of health and illness defy the biomedical model of disease as many of them are ‘concerned with the social origins and influence on disease’ rather than pathological reasons only. There are five sociological perspectives of health and illness: Social Constructionism, Marxism, Feminism, Foucaulian analysis, and Functionalism. These different sociological perspectives were critically analyzed through this article as for better understanding of conceptualize management of health services Social Constructionism is a sociological perspective focus on the sociology of knowledge and reality. Marxism focuses on equity between social classes and emphasizes inequality in capitalist society. According to Marxism inequality of distribution healthcare services in capitalist society arise from the marginalization of some categories of the population who do not contribute to economic system. Feminist theory is to understand and explore the multiple and various reasons for inequalities between the genders. In the healthcare sector, feminists believe that healthcare organizations are hierarchical systems, where doctors (usually men) are at the top level while nurses (usually women) have a lower level of importance. Main areas that Foucault theory emphasizes are power, knowledge and discourse. Foucault believes that there is a relationship between power and knowledge. This relationship appears clearly in the health field, as medical professionals comprise a group of people who have special knowledge (medical knowledge) and they gain the power from this knowledge. Finally, functionalism is a sociological perspective that describes society as a system made up of ‘interconnected and interrelated parts’ and it highlights the relationships between different parts of society In conclusion, the five sociological perspectives provide holistic picture about conceptualization of healthcare systems.

KeywordsSocial Constructionism, Marxism, Feminism, Foucaulian analysis, Functionalism

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Perforated Jejunal Gastrointestinal Stromal Tumor(GIST) Presenting as Acute Abdomen: A Rare Presentation

Abstract— Gastrointestinal stromal tumors (GIST) are rare neoplasms of the gastrointestinal system. A case of 40 year old man having tense tender abdomen with obliterated liver dullness and shifting dullness was presented in emergency, it was further investigated on X rays, where pneumoperitoneum was found. This case was then decided to go for Laparatomy after routine investigations to further explore. On exploratory laparatomy, diffuse peritonitis with brown coloured fluid was observed. A 10 x 5 x 7 cm mass was found having an opening communicating with the gut lumen was present around 10 cm from the ligament of treitz. However, no adjacent structures, liver or parietal peritoneum seemed to be involved. Gross examination of the specimen revealed an outward bulging mass, which was centrally necrotic and contained hemorrhagic-necrotic material. On histo-pathological examination, features suggestive of gastrointestinal stromal tumor (GIST) with mixed spindle and epitheoid pattern was seen. Mitoses were slightly increased (<5/10' HPFs) leading to the conclusion of LOW GRADE GIST with tumor free margins of gut (R0 resection). So it was a case of Gastrointestinal stromal tumors (GIST), which is a rare medical presentation. So it was decided to report this case as a rare case presentation.

Keywords: Gastrointestinal Stromal Tumors (GIST), Neoplasms, Gastrointestinal system

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Microbiological Study of Pharyngitis at a Teaching Hospital, Chinakakani, (Andhra Pradesh) India

Abstract—The aim of the study was to observe the prevalence of various microorganisms from throat swab specimens in patients attending a tertiary care hospital at Chinakakani, Guntur. Throat swab specimens were collected aseptically from 100 patients and cultured on appropriate bacteriological media. Isolates were identified by biochemical tests & antimicrobial susceptibility performed by standard methods. Out of 100 Samples, culture was positive in 25 samples. So Bacterial infection was found in 25% of Pharyngitis. Streptococcus pyogenes was the commonest isolate, followed by Staphylococcus aureus and Candida albicans. Majority of bacteria were Streptococcus pyogenes, Staphylococcus aureus and Candida albicans. In 60% it was mixed infection. The susceptibility patterns varied depending on the drugs, but most of the organisms were susceptible to penicillin, erythromycin and vancomycin. Improved personal hygiene and health education of the masses on how to care for ear, nose and throat will greatly reduce these microbial infections. This study will be useful for control strategies and for predicting pathogen prevalence in throat swabs.

Keywords Pharyngitis, Streptococcus Pyogenes, Throat Swab

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Factors associated with Dementia with special reference to Serum Homocysteine Level: A Case-Control Study

Abstract—Prevalence of degenerative dementias and dementias associated with cerebrovascular disease is increasing with the time. Dementia is one of the most significant public health problems. Demographic data, medical history, general biochemical data and serum total homocysteine (tHcy) levels was used in this study to examine the differences between dementia and normal control groups. A cross-sectional study was conducted on 236 individuals who were above the age of 65 years. These participants went through the Mini-Mental State Examination (MMSE), Clinical Dementia Rating (CDR), demographic characteristics, biochemical data and tHcy level. Each of the above mentioned factors was assessed. There were significant differences in the history of hypertension, diabetes mellitus, marital status, alcohol consumption (AC), BMI value, and triglyceride (TG) and serum tHcy levels. The logistic regression analysis showed significant differences in marital status, AC and tHcy. So it can be concluded that elevated serum tHcy, no AC and no partner are associated with the risk of dementia in elders of Southern Taiwan. It needs further researches to identify and reduce the risk of dementia.

Keywords: Dementia; Homocysteine; partner; alcohol consumption.

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Morphometric study of Sacral Hiatus for Caudal Epidural Block

Abstract— Study of variation of sacral hiatus in dry bone is important as it determines access of sacral hiatus for caudal epidural anaesthesia and analgesia. So this descriptive observational study was conducted on 80 adult sacrum bones were studied at department of Anatomy, SMS Medical College, Jaipur with the aim to examine Morphometry of Sacral hiatus including shape, length, A-P diameter at apex and transverse width at base. Most commonly found shape of sacral hiatus in this study was inverted U/V shape. Length of sacral hiatus ranged 6 to 43 mm with more than half cases having length between 10-20 mm. Most sacrum (81.25%) had anterio-posterior diameter of 4 to 8 mm. Half of the sacrum had transverse width at sacral cornua between 9-13 mm. It can be concluded that anatomical variations in sacral hiatus are cause of caudal epidural anaesthesia failure and procedure related complications. Understanding these variations may improve success of caudal epidural anaesthesia and decrease incidence of complications. So this study will be useful to increase success rate of epidural anaesthesia.

Keywords Sacrum, Sacral hiatus.

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Medical Journal: IMJ Health: Volume-2, Issue-7, July 2016

Medical Journal July 2016 Issue

Glycolic Acid Peels Versus Salicylic Acid Peels in Atrophic Acne Scars : A Randomized Comparative Study

AbstractScarring is a well recognized sequel of acne. Because of the prevalence of acne scarring and strong negative emotions it engendering affected patients, several approaches have been developed for its treatment with varying success rates. Glycolic acid 50% peels and Salicylic acid 30% Peels are classified as superficial peel and are consider safe in Indian patients. While chemical peels are widely being used in India for various indications. There is a paucity of published studies on the efficacy of chemical peel specifically for acne scars in Indian patients.

Purpose of this study was to evaluate and compare the effectively of these two agents in the treatment of acne scars. Eighty cooperative patients[≥18 years age]with predominantly moderately atrophic acne scarring were randomly divided into 2groups of 40each.Patients of group A received Glycolic acid peels and patients in group B, Salicylic acid was used at 3weeks interval for four sessions. Objective evaluations of treatment response. Subjective assessments of treatment response were also done separately by the researcher, an independent observer and the patients separately.

Both of agents led to significant reduction in the total acne scar score[p< 0.05]but no significant difference was noted between the two peels. Side effects were lesser with Salicylic acid peel.

Hence conclusion was drawn that both 50% Glycolic acid and 30% Salicylic acid peels are safe in Indian skin and equally effective in the treatment of mild to moderate acne scarring.

Keywords Acne Scare, Acne Peels, Glycolic acid peel, Salicylic acid peel

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Effect of Root Heal Therapy (RHT) on Asthma: A Quincy Experiment

Abstract—Asthma is a chronic inflammatory disease of the airways that affects people of all ages. It may manifest as severe attacks, which can require urgent health care. It causes limitations in daily activities, loss of school and work days, lung function impairment, reduced quality of life, and an adverse socioeconomic burden. There is no cure of asthma, once it is diagnosed it can be managed by a good treatment plan, so that patient can live a better quality of life with the disease. This present study was planned to compare the effect of traditional treatment alone and in combination with Root Heal Therapy on asthma cases. A Quincy experiment was conducted on 60 patients of Asthma, who were taking treatment from a physician working in Jaipuriya Hospital, Jaipur. Out of these 60 asthama patients who were receiving traditional treatment, 30 patients were given this RHT along with traditional treatment. Baseline status of asthma and Asthma Quality of life Questionnaire (AQLQ) was assessed. These cases were followed for 18 months, again they were assessed as per AQLQ. Changes in status of asthma in both the group over this period were compared with Chi-square test and Unpaired 't' test. It was found that significantly more cases were benefited with this RHT in the form of number of spells of asthma, duration of illness due to asthma, mean days of activity loss and proportion of cases needed hospitalization during last one year. Pulmonary Function test were also better in experimental group than control group. Although mean number of eosinofills decrease was also found higher in experimental group but it was not found significant. It is concluded that Quality of life of these asthma cases were significantly improved on physical, emotional, social and occupational domains of life in cases with RHT than the cases only on traditional treatment.

Keywords Asthma, Root Heal Therapy (RHT), Pulmonary function tests, Asthma Quality of life Questionnaire (AQLQ).

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Association of Tuberculosis and Biochemical Nutritional Status A Case-Control Study

AbstractPulmonary tuberculosis is a very infectious disease and is a public health problem specially in developing country like India. Association between tuberculosis and nutritional status is assumed by various authors at time to time. So this present study was aimed to where there is any association between tuberculosis and nutritional status of individual. For study purpose 40 newly diagnosed tuberculosis taken in one group (Group A), 30 cases of relapse cases of tuberculosis in group 'B' and 30 matched healthy controls in group 'C'. Protein and micronutrient levels of each of the subject were assessed and compared group wisely. Significance of difference was inferred by Unparied 't' Test. It was found in this study that Protein, Albumin, Alkaline Phosphatase and Vitamine D were significantly lowered in Tubercular cases than controls. So it can be concluded that tuberculosis is more common in nutritionally deficit individuals.

Keywords: Tuberculosis, Nutritional Status, Protein Level, Macronutrient Level.

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Socio demographic profile of Diabetic cases attended at Diabetic clinic of a tertiary hospital of western Rajasthan India

AbstractDiabetes Mellitus is a lifestyle disease it is increasing with increase of urbanization. It is a side effect of development. Nowadays with the development of community it is also on increase trend. So this study was conducted on 250 patients of diabetes attended at Diabetic Clinic of SMS Hospital Jaipur, with the aim to find out socio-demographic profile of these diabetes cases. General information about the these case was gathered in a pre-designed semi-structured performa. It was found in this study that majority of cases were in age group of 31 to 45 years with slight male dominance. Education wise majority were Graduate followed by secondary educated and others. Likewise occupation wise majority were either unemployed of professional. Majority of cases were from Socio economic Class II and III. So it can be concluded that diabetes is a disease of middle age slight male dominance and of educated middle class individuals. Further studies are required to establish this fact.

Keywords Diabetes Mellitus, Socio-demographic profile

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Acute Illness episodes and Limitation of Daily Activity of Life in Geriatric population in Jaipur: A Period Prevalence Study

Abstract Elderly population is increasing due to demographic shift in favor of geriatric population. This age group is susceptible for many acute and chronic health problems which may lead to limitation daily activities of life. Study of acute and chronic health problems with limitation daily activities of life of this population is required to frame comprehensive policies to make ageing a comfortable experience. So this cross-sectional period prevalence study was carried out from September 2009 to August 2010 on 1620 elderly residing in Municipal corporation area of Jaipur city with the aim to study episodes of acute health problems within last one month and limitation daily activities of life within last years of this population of elderly population. Study population consist of 1620 elderly with M:F ratio 0.95. Mean age of elderly was 66.08 years with slight female predominance i.e. 1048 females for 1000 males in Jaipur city. It can be concluded from 41.6% of elderly were having difficulty in performing activity of daily living and this difficulty was found more in females that males and in older ages. It was also revealed that 44.37 of elderly had one or more episodes of acute illness in last one month. These number of episodes of acute illness in last one month was found more in males and in older age groups.

Key words- Elderly, Geriatric, Acute Illness, Daily activities of Life.

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Friday, 1 July 2016

IMJ Health : June 2016

Medical Journal June 2016 Issue

A Survey of Sexual Knowledge, Attitudes, Desire and Behavior among University Students

AbstractSexual health (SH) and sexual behavior of young people have become a growing public concern. But few studies have been conducted to investigate the prevalence and psychosocial correlates of this phenomenon.

Purpose: To understand college students’ sexual knowledge (SK), sexual attitudes (SA), sexual desire (SD) and sexual behavior (SB).

Methods: A self-reported questionnaire survey on SK, SA, SD, and SB was conducted among 520 university students. Their demographic data, SK, SA, SD, and SB were assessed.

Results: A total of 500 students completed the questionnaire. The SKS total score had a mean of 23.05; 105 (21.0%) subjects had had premarital sex; 121 (24.2%) had a partner; 117 (23.4%) had a medical educational background. The results demonstrated an increased risk of premarital sex amongst males and subjects with the risk factors of smoking, drinking, having a partner, and having higher levels of SD and SK and more open SA.

Conclusions: This study provides support for the idea that university students lack SK (especially regarding contraception knowledge), even though the students had a medical educational background. Additionally, a considerable amount of them engaged in premarital SB. Our findings also suggest that university students need sex education, particularly in combining sexuality with their life, in relating to others maturely as a sexual individual, in employing contraception, and in preventing sexually transmitted diseases (STDs). Our study suggests that interventions aimed at expanding university students’ SK and other related skills are required.

Keywords-- University students; Sexual behavior; Sexual knowledge; Sexual attitude

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Hutchinson – Gilford Progeria Syndrome with associated hypothyroidism: A rare case report

AbstractHutchinson–Gilford Progeria Syndrome is a rare genetic disorder characterized by premature aging involving the skin, bones, heart, and blood vessels. We report a five year old female child with clinical manifestations characteristic of this syndrome. This child had a senile look with large cranium, frontal bossing, sparse light brown hair and dilated visible veins over the scalp. Other features were prominent eyes, beaked nose, micrognathia, sclerodermatous changes in both feet and legs, laxed and atrophic skin over dorsum of both hands and mottled pigmentation over trunk. Decreased high-density lipoprotein (HDL) levels was characteristic of the syndrome. This case is reported for its rarity and uncommon relationship with hypothyroidism.

Keywords: Hutchinson, Gilford Progeria Syndrome, Hypothyroidism.

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Comparison of Corneal Endothelial Cell Counts in Patients with Controlled Diabetes Mellitus (Type 2) and Non Diabetics after Phacoemulsification and Intraocular Lens Implantation

AbstractCataract is the main cause of blinding and Diabetes Mallitus (DM) is the one of major cause of early cataract. Patents of DM has poor So this study is aimed to assess the corneal endothelial cell count in patients of DM (Type 2)after phecoemulsification and intra-ocular lens implantation. This study was conducted on 66 patients of cataract, out of which 33 patients with and 33 without DM (Type 2). Both groups underwent pre operative investigation and ophthalmological assessment and then undergo phacoemulsification done by same surgeon. After phacoemulsification all cases were followed up on 1st day ,1st week,1 month and 3 months and Uncorrected visual acquity (UCVA), Best corrected visual acquity (BCVA),corneal thickness, endothelial cell count and morphometric analysis were recorded. Both groups parameters were compared with unpaired 't' test. At the end of 3 months it was found that the mean endothelial cell loss in Group A(Diabetic) was 6.9% ± 0.6 and in Group B (control) was 2.4% ± 0.3 suggesting that the corneal endothelium in diabetic patients is under metabolic stress, and weaker against mechanical loads, such as phacoemulsification, than that in non-diabetic subjects. Despite good glycemic control and no corneal abnormalities before surgery. Endothelium in diabetic subjects is more vulnerable to surgical trauma and has a lower capability in the process of repair. These findings should be considered when planning cataract surgery in patients with diabetes.

Keywords: Diabetes Mellitus Type 2, Glycemic Control, Corneal Endothelial Cells, Phacoemulsification, Cell Repair.

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Awareness of Infant Feeding: Nursing Program Student Survey

AbstractChild nutrition is an important factor for their physical and neuro-psychological development and overall health not only in childhood but also in adulthood. The World Health Organization recommends that mothers should be informed about the advantages and the enormous benefits of breastfeeding. It is part of the professional responsibility of nurses to promote good health care habits among women in fertile age and raise the overall health awareness of parents. The aim of the study was to research the knowledge of infant feeding among students in the Nursing Program. An anonymous survey was conducted among students in the Nursing I class. The survey group included a total of 51 students, ranging from 19 to 47 years old. All analyses were conducted using Statgraphics Plus software, version 2.1. It was found that students rate the advantages of breastfeeding for the mother as follows: faster recovery (29.4%); reduces the risk of cancer in women (21.6%), faster recovery of the weight of the mother before birth (27.5%). The majority of students were able to point out specific steps to successful breastfeeding and the respective time schedules of infant feeding (70%). The study found less satisfactory results of the participants’ knowledge on how to prepare infant dairy blends 19 (30.3%) and the duration of breastfeeding in 11 (21.6%). It can be concluded that students in the Nursing Program demonstrate good knowledge of infant nutrition.

Keywords: Infant Nutrition, Health Awareness Promotion, Student Knowledge, Nurse, Education.

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Relation between Type of Architecture, Interpersonal Relationship and Spiritual Health of Resident

AbstractBy providing proper architecture as per the need and behaviour of the individuals a person may be satisfied with surrounding that may affect spiritual health of individual and in turn the overall health. So this study was conducted on two type of housing society with the aim to find out relationship between type of architecture, interpersonal relationship and spiritual health of their residents.

Methodology: A comparative observational was conducted on two type of housing society having same SES status class I but with different type of architecture. Various components of architecture of their houses was assessed of these houses and general information gathered from head of family. Interpersonal relationship of societies was assessed by applying 9 itemed self reported Relationship Structures (ECR-RS) questionnaire for neighbors on head of family. Spiritual health of head of family was assessed with Spiritual Health Assessment Scale (SHAS). The relationship between type of architecture, interpersonal relationship and level of spiritual health was inferred by Chi-square test and Unpaired 't' test.

Result & Conclusion: It was also found out that Interpersonal relationship were significantly better of society having architecture preferring more of comfort and ambiences than safety and vice versa. Likewise spiritual health score was observed significantly higher in occupants having architecture preferring more of comfort and ambiences than safety and vice versa.

Keywords— Architecture, Interpersonal Relationship, Spiritual Health

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Association of Spiritual Health and Psycho wellness in First MBBS Students

AbstractSpiritual health is not given its due importance since long time. But nowadays modern medicine is seen in relation to spiritual health. and studies were conducted to find out its effect in various diseases. So this study was conducted on medical students of SMS Medical College, Jaipur (Rajasthan) India. aimed to assess the spiritual health and its association with psycho wellness. A cross-sectional study was conducted on 1st MBBS students present on the day of survey were given spiritual health assessment scale (SHAS) to assess the their spiritual health. Then these students were screened through Modified Mini Scale (MMS) to found out zone of psycho wellness i.e. red and orange zone of psycho-wellness. Association was inferred by Chi-square test and ANOVA with Post-hoc Tukey test. Out of 230 students attend on the day of survey, majority of students i.e.164(71.3%) were having good spiritual health. Likewise only 132 students (57.39%) were in green zone (no disease zone), while 36(15.65%) students were in orange (borderline) and 62 students (26.96%) were in red zone (Psychiatric disease zone) of psycho-wellness. On analysis it was found that Mean scores of spiritual SHAS of green zone was significantly high than mean SHAS scores of other zones. Majority of students were having poor spiritual health and this spiritual health was strongly associated with psycho-wellness of students. Poorer the spiritual health of students leads to poorer the psycho-wellness of students.

Keywords Spiritual health, Psycho-wellness, Spiritual Health Assessment Scale (SHAS), Modified Mini Screen (MMS), Medical students

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Tuesday, 7 June 2016

IMJ Health : Volume-2, Issue-5, May 2016

Medical Research Journal

Idiopathic Linear Calcinosis Cutis - A Case Report

AbstractLinear calcinosis cutis is a very rare disorder; reported in association with lichen sclerosus atrophicus, scleroderma, after intravenous infusion of calcium and acute monocytic leukemia. In available literature idiopathic Zosteriform Calcinosis Cutis is yet to be described. Eight year old child presented with spontaneous painful, slowly progressive, linear band like nodules over right half of the chest and back of trunk. It is a rare presentation in Skin Department. On the basis of clinical, laboratory investigation and histopathology a diagnosis of Linear Calcinosis Cutis was made. So it was decided to report this rare case of idiopathic Zosteriform Calcinosis Cutis because of unusual presentation and rarity of the disorder.

Keywords: Linear Calcinosis, Zosteriform Calcinosis Cutis, LSA, Scleroderma.

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Survival Rate of Teeth after Replantation of permanent incisors in Relation to defined Parameters: An Interventional Study

AbstractTreatment of severely traumatized teeth is known to be a challenge in oral surgery. In particular, severe tooth trauma in children is difficult to treat, mainly because of damage to the periodontal ligament, unphysiologic storage of the tooth and the growing jaw of these patients.

In this present clinical study, teeth with severe trauma were treated using an extra-oral endodontic method. Auto-alloplastic replantation involves using a titanium post as endodontic filling prior to replantation. Aim of this study was to determine survival rate of such replanted permanent teeth in relation to defined parameters that may influence survival. In this study, 44 patients with 58 replanted teeth were evaluated.

Out of 58 teeth, 28 were avulsed and 30 teeth were dislocated; 24 teeth healed with a functional periodontal ligament (functional healing), 8 teeth healed with ankylosis and a further 8 showed replacement resorption. Infection-related resorptions were present in 2 teeth, which were removed after two months. Other 16 cases could not be assessed. 5-year survival rate according to Kaplan-Meier analysis was 83.9% and estimated time of survival was 88.5 months. Avulsion and storage had no significant effect on tooth loss (p=0.178). Mature teeth had a significantly higher 5-year survival rate (92.2%) than immature teeth (72.4%, p = 0.041, log rank test).

It can be concluded that auto-alloplastic replantation is a reliable method in dental trauma treatment. This method is suitable with a high rate of success for avulsed or severely traumatized teeth.

Keywords: Dental Trauma, Avulsion, Replantation, Extra-Oral Endodontic Treatment.

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School Based Filaria Transmission Assessment Survey at Purba Medinipur District, West Bengal; India in 2014

AbstractLymphatic Filariasis is one of the neglected tropical diseases of world. India was set a target to eliminate lymphatic filarial within the year 2015 by administering Mass Drugs Administration (MDA) with diethyl carbamazine and albendazole for five consecutive years. MDA coverage was more than 80% - 92% of different MDA rounds in Purba Medinipur district. Impact of MDA programme was assessed by searching microfilaria through night blood survey. Prevalence of microfilaria was 2.4% to zero in all sentinel sites. Finally transmission assessment survey (TAS) as per WHO guidelines - 2011 of microfilaria was conducted on September and October’ 2014 among student of class I and II for making decision to stop or continue MDA. This district was sub-divided into three evaluation units (EUs), named Evaluation Unit-I, Evaluation Unit-II and Evaluation Unit-III to implement TAS programme. Sample Survey Builder (SSB) tool was used for sampling. Cluster survey was conducted with critical cut off value 20 in each EU. Immuno-chromatographic test (ICT) card was used to detect microfilaria among school students of class I and II (6 - 7 years age). All students of class-I and II of selected school were tested with ICT card, no sampling interval. Among the total enrolled school student of class-I and II, 3.67% were tested for microfilaria with ICT card. Among them, 51.3% were boys and 47.3% were girls. Out of total 5108 children surveyed only three (0.06%) was found positive for filarial antigen. All three cases had migratory history to filaria endemic areas and remain with relatives for >11 months. As proportion of positive cases did not cross the critical cut off value. So these three Evaluation Units were qualified to stop further MDA.

Key word: Microfilaria, Transmission Assessment Survey, Purba Medinipur, West Bengal.

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Treatment Therapies in Renal Cell Carcinoma in elderly: A Descriptive Analysis

AbstractKidney cancer accounts for 63% of cancers that affect the elderly and access to innovative therapies are needed to diagnose and treatment. So this study was conducted with the aim to find out the type of better therapy in renal cancer in elderly. This study was conducted on 21 cases of renal cell cancer in first group and 64 cases in group II . Use of humanized monoclonal antibodies administered at a dose of 10 mg / kg in combination with the alpha allIFN 9 (MUI) dose subcutaneously three times a week for three months with a positive response at 12 months in 91% of cases. AC of the kidney is a typical disease of geriatric and the prognosis is greatly influenced by other underlying conditions, surgery is the treatment of choice healing while finding difficulty in implementing patient with: renal insufficiency, solitary kidney, or in 30% of cases (occasional) in late-stage cancers. the chemotherapy used in association to IFN led to a partial response in the progression of the disease 15% of cases. Results show that in these cases treated with this therapy had encouraging results in terms of complete response, partial response and stable disease. Disappointing results reported (chemo, radio,) in this study have led to the use of biological response modifiers establishing itself as the treatment of choice (first results) in advanced kidney cancer, in combination with lIFN 2alfa. Additional molecular biology studies are useful for better understanding of the mechanisms that regulate the aging process and the onset of illness in old age.

Keywords- Renal Cell Cancer, Surgery, Chemotherapy, Radiotherapy, Geriatrics.

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Internet Addiction Pattern among High School Students of Jaipur City: A Descriptive Study

Abstract This present study was conducted on high school students to find out patterns of internet use and prevalence of Internet addiction among high school students. Seven hundred students of three English medium schools of Jaipur city were selected by convenient sampling technique who returned the completed forms. Young’s Internet Addiction Test (IAT) Internet addiction or problematic Internet use was considered when IAT score was ≥50. Out of these 700 students surveyed, 250 (28.57%) students were having Internet addiction. Internet Addiction was found significant more (p < 0.05) in males, prolonged users, and younger age of exposure to Internet and high socioeconomic status than their counterparts. In near future Internet addiction may be an important clinical entity. It needs extensive research. All high school students must be screened for Internet addiction and vice versa.

Keywords: Internet, Students, Internet Addiction Test

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Effect of Mifepristone on Uterine Fibroid with special reference to Symptoms and its Size

Abstract: Uterine Fibroids are most common growth of female reproductive tract in premenopausal women. Non surgical treatment options for this have limitations. So this Prospective interventional study was conducted to evaluate the effect of low dose Mifepristone treatment for 3 months on fibroid size and related symptom.

Patients: Twenty five patients with symptomatic fibroid, aged 20-50 years.

Intervention: Patients received 10mg Mifepristone daily for 3 months

Method: Baseline data regarding fibroid volume, Hb value, PBAC (Pictorial Blood Assessment Chart) & VAS (Visual analogue Scheme) score were recorded and these data regarding above parametres again collected at the end of 1st month & 3rd months of therapy.

Results: Mifepristone treatment significantly reduced fibroid mean volume from 91.13cm3 at enrollment to 38.73cm3 after 3months of treatment. Mean PBAC score was reduced for 111.52 at enrollment to 2.36 at the end of 3rd month of therapy. At 3 months 22 of 25 case (88%) developed amenorrhoea. At the end of therapy hemoglobin mean value was raised by 2.38 gm/dL from the baseline mean value of 8.70mg./dL. There were no major side effects during the course of the study and treatment was well tolerated.

Conclusion: Low dose Mifepristone (10mg) reduces fibroid size and related symptoms with no side effects among women with symptomatic fibroids.

Key Words: Mifepristone, Leiomyoma, Fibroid Volum, Menorragia and Amenorrhoea

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Effect of custom made splint in first carpo-metacarpal joint Osteoarthritis: A Quincy Experiments

Abstract Custom- made splints are in use of treatment of osteoarthritis but there are very few studies in this regards i.e. effectiveness of use of these custom-made splints. So this present Quincy experiment interventional study was conducted to evaluate the effectiveness of custom-made splints (short dynamic splint) on pain, function, grip strength and key pinch in patients with first carpometacarpal (CMC) joint OA (grade 2nd and 3rd) in comparison to conventional treatment. Sixty patients with CMC joint osteoarthritis were randomly assigned to the splint (group A) or non splint group B) treatment. So 30 CMC joint osteoarthritis patients (grade 2nd and 3rd)were given custom-made splints (short dynamic splint)and 30 CMC joint OA (grade 2nd and 3rd)were given conventional treatment. Both groups were comparable statistically in both the groups (P>0.05) as per age, sex etc. In follow up assessment at 4th & 8th week, the Splint group shows significant improvement in all the outcomes (pain, grip and pinch strength) measures at all follow up except DASH score improvement at 2nd follow up in comparison to non splint group. So it can be concluded that the splint group shows significant improvement in all the outcomes (pain, grip and pinch strength) measures at all follow up except DASH score improvement at 2nd follow up in comparison to non splint group. Result of present study supports that rehabilitation intervention (Short Custom-Made splint) can significantly benefits to individuals with early osteoarthritis and by it we can delay the need for surgical intervention.

Keywords: CMC joint osteoarthritis, custom-made splints.

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Awareness and Perception of Sexually Transmitted Disease (STI) in females: A cross sectional study

AbstractReproductive tract infections (RTIs) including sexually transmitted infections (STIs) is a public health importance as it adversely impacts the reproductive health of people. So this present study was conducted on 360 females of slum area of Jaipur city to assess the awareness about STI/RTI and their perception and practices. Prevalence of RTI/STI among females (15-49 years) of slum area of Jaipur was found 38.2%. Awareness regarding symptoms of RTI/STI, mode of its spread and its prevention was 39.7%, 33.6% and 28.6% respectively. Regarding treatment seeking behavior for RTI/STI more women from higher socioeconomic status as well as higher educational status were opting for taking treatment. This awareness not found to be affected by literacy level of females.

Perception and practices regarding choice of health facility for treatment of RTI / STI, it was observed that 57.8% females were of opinion that treatment for RTI / STI should be taken, 32.5% of the females actually took the treatment and 42.2% of females believed that there is no need of treatment. Maximum females (23.6%) believed that treatment should be taken from lady doctor. Among those who took the treatment, half (42.3%) of them took treatment from lady doctor.

Keywords: Reproductive Tract Infections (RTIs), Sexually Transmitted Infections (STIs), Awareness, Perception and Practices.

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