Abstract— Acute Generalized Exanthematous Pustulosis (AGEP) is a rare severe cutaneous adverse reaction mainly caused by drugs. It is characterized by an acute pustular eruption over the body along with fever and leukocytosis. It has been known to resolve spontaneously over a period of 2-3 weeks without long term sequelae. However it is of utmost importance for the physicians to clinically identify this condition as to prevent unwanted extensive management. Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAIDs) prescribed over the counter for pain relief. A sixteen year old boy is reported here who developed AGEP after taking mefenamic acid for fever and joint pain. It was diagnosed with the help of history, clinicopathological correlation, AGEP validation score and recovery on withdrawal of the drug. To the best of our knowledge this is the first case report of mefenamic acid causing AGEP in the literature.
Keywords: Mefenamic acid, Acute Generalized Exanthematous Pustulosis, AGEP.
Abstract—Organ donation is very important action by which a life can be saved, so it is advisable to determine fill the formalities for organ donation at least at the time of death. But due to lack of awareness along with myths and misconceptions add to the low percentage of organ donation in India. So this descriptive study was carried out on 815 more than 18 year aged participants with the aim to assess the willingness for organ donation in participants with reasons for willingness as well as for unwillingness. It was found willingness for donate their organ were only in 50.4% of participants whereas 20.9% did not want to donate and 28.7% did not decide. The most common reason found for willingness in this study was ‘I could save many life from donating my body' i.e. in 80.8% followed by ‘After death I will be alive' response (51.5%), ‘It’s saintly work' response (50.6%), 'Society will be benefited' response in 42.2% and 'On being motivated by media and people ' response in 35.8% of participants. And when reasons for not willing to donate their organ was discovered in this study, it was found that majority (55.9%) could not explain any reason for that while 17.1% were feared that family and doctors will not save them, 14% said that family members will sell their organ (14.0%) and few (12.9%) said that it’s against my religion. It can be observed that a quantifiable (35.8%) of participants were motivated for willingness for organ donation through media and people are having myths regarding organ donation. So to promote organ donation, awareness for organ donation and its related issues should be encouraged through various medias.
Keywords: Organ Donation, Willingness.
Prevalence of Post-operative Surgical site infection in a district Hospital of western Rajasthan India
Abstract— Wound infection is the second commonest complication of wound healing. This study was carried out on 250 post-operative cases operated at a district hospital of western Rajasthan, India with the aim the aim to find out prevalence of post-operative surgical site infection and its causing organism. After taking personal information and detailed clinical, operative and post-operative history of these cases, swab from post-operative wound was taken and sent for culture and sensitivity test in Microbiology. Association was inferred with Chi-square test. Post operative surgical site infection rate was found 11.6 % which was found significantly more in intestinal surgeries than the other. Most common causative organism for infection was Staphylococci cases followed by Streptococci, E. Coli and Klebsella. Out of total 11.6% infected cases, majority (8.8%) of patients had infection with more than one organism only 2.8% were having single organism.
Keywords— Post-operative surgical Site Infection (SSI), Micro-organism, SSI Infection Rate.
Comparison of Resistance and Sham Training of Expiratory Muscles on Pulmonary Functions in Patients with Spinal Cord Injury: An Interventional Study
Abstract— Respiratory complications are major sources of morbidity and mortality in spinal cord injury (SCI). Improvement in expiratory muscle strength may be associated with improved cough and clearance of secretions. So that expiratory muscle training are advised in SCI cases to improve expiratory muscle strength. This study was conducted to compare the effect of Resistance and Sham training on pulmonary function test in spinal cord injury cases. It was found the mean value of all the parameters of PFT of Sham training was found to increase from baseline to 1st and 2nd follow up. This difference was found significant in all the parameters of PFT at 2nd follow up, but FEV1 and PIFR of 1st follow up (p value < 0.05) only. Likewise, it is also observed that the mean value of all the parameters of PFT of test group was found to increase from baseline to 1st and 2nd follow up. This difference was found highly significant (p value <0.001) in all the parameters of PFT at 1st and 2nd follow up. So it can be concluded that however both the type of training improve PFTs but the improvement of high resistance training was significantly more than they were for sham training.
Keywords: Spinal Cord Injury (SCI), Pulmonary Function Test, Resistance Training and Sham training.
Abstract— This study was conducted to find out the impact of menopausal transition symptoms on quality of life and eating behavior in west Algerian women.
Subjects and methods: A prospective cross sectional survey was conducted between February 22 and April 30, 2016 in Oran (west Algeria). Eighty (48±2 years) perimenopausal women participated to the study. A structured interview survey was developed on socioeconomic level, climacteric symptoms and quality of life. Daily energy expenditure (DEE) was assessed by an adapted questionnaire and food intake by a 24h "Recall and Record".
Results. Hot flushes, night sweats, palpitations, anxiety, headaches, memory loss and insomnia were the symptoms feeling by women. The quality of life assessment showed that 53% had a moderate quality of life (10 to 15 symptoms), 16% with poor quality of life (16-20 symptoms) whereas 25% had a good quality of life (5 to 10 symptoms) and 6% of women had an excellent quality of life (≤ 5 symptoms). At this time of the menopausal transition, 64% reported modification in their eating behavior.
Conclusion: Clinical symptoms of perimeanopausal period influence the quality life of women on menopausal transition.
Keywords: Perimenopause, Quality of life, Behavior food.